| Registro completo |
| Provedor de dados: |
Anais da ABC (AABC)
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| País: |
Brazil
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| Título: |
Control of the skin scarring response
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| Autores: |
Ferreira,Lydia M.
Gragnani,Alfredo
Furtado,Fabianne
Hochman,Bernardo
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| Data: |
2009-09-01
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| Ano: |
2009
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| Palavras-chave: |
Wound healing
Keratinocytes
Fibroblasts
Keloid
Tissue engineering
Skin
Plastic surgery
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| Resumo: |
There comes a time when the understanding of the cutaneous healing process becomes essential due to the need for a precocious tissue repair to reduce the physical, social, and psychological morbidity. Advances in the knowledge on the control of interaction among cells, matrix and growth factors will provide more information on the Regenerative Medicine, an emerging area of research in medical bioengineering. However, considering the dynamism and complexity of the cutaneous healing response, it is fundamental to understand the control mechanism exerted by the interaction and synergism of both systems, cutaneous nervous and central nervous, via hypothalamus hypophysis-adrenal axis, a relevant subject, but hardly ever explored. The present study reviews the neuro-immune-endocrine physiology of the skin responsible for its multiple functions and the extreme disturbances of the healing process, like the excess and deficiency of the extracellular matrix deposition.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300024
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| Editor: |
Academia Brasileira de Ciências
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| Relação: |
10.1590/S0001-37652009000300024
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| Formato: |
text/html
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| Fonte: |
Anais da Academia Brasileira de Ciências v.81 n.3 2009
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| Direitos: |
info:eu-repo/semantics/openAccess
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